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1998年4月在河北省石家庄、张家口和承德市开展了麻疹疫苗（MV）的初始强化免疫．结果显示：三市共登记所辖区域内8月龄～14岁儿童3312425人，接种2896297人，接种率87.44％；石家庄、张家口、承德市的接种率分别为84．85％、90．26％和91．93％．分年龄统计，2岁接种率最高，为93．88％;10-14岁最低，为83．71％．学龄前儿童接种率高于学龄儿童，小学生的接种率高于中学生，流动儿童接种率高于本地儿童．各县（区、市，下同）报告接种率相差悬殊，有4个县（8％）＜60％，最低仅40％．分析接种率较低的原因，与部分县接种时出现异常反应，一些意外事件的影响，以及一些基层卫生人员工作责任心差等主客观因素有关．由于MV初始强化免疫人数多，持续时间长，现有的冷链设备不具备在短时间内储存大量MV的能力，这些都为今后继续开展MV强化免疫工作提供了可借鉴的经验和教训．
In April 1998, the initial boost of measles vaccine (MV) was carried out in Shijiazhuang, Zhangjiakou and Chengde in Hebei Province. The results showed that 3,312,425 children aged 8 months to 14 years were registered in the three cities and 2896,297 were inoculated with a rate of 87.44%. The vaccination rates in Shijiazhuang, Zhangjiakou and Chengde were 84.85% and 90.26% respectively, And 91.93%. According to the statistics of age, the highest vaccination rate was 2 years old, 93.88%; the lowest was 10-14 years old, 83.71%. The vaccination rate of preschool children is higher than that of school-age children, the vaccination rate of primary school students is higher than that of secondary school students, and the vaccination rate of migrant children is higher than that of local children. The counties (districts, cities, the same below) reported a huge difference in vaccination rates, with 4 districts (8%) <60% and a minimum of only 40%. Analysis of the reasons for the lower rate of vaccination, and some counties inoculated when there is an abnormal reaction, the impact of some accidents, as well as some primary health workers work responsibility and other subjective and objective factors. Due to the large number and long duration of MV initial immunization, the existing cold chain equipment does not have the ability to store a large number of MVs in a short period of time, all of which provide experiences and lessons learned for continuing to carry out MV intensive immunization work in the future.