本文介绍10例特发性急进性肾小球肾炎病人,均有蛋白尿、血尿及尿沉渣红细胞管型,肾功能进行性丧失,以及肾活检60%以上肾小球有上皮细胞新月体。经较全面检查并已排除能引起新月体肾小球肾炎全部疾病。采用甲基强的松龙1g/24h 静脉内“冲击”7日,后改用口服强的松,开始80mg/日,7日后减至60mg/日,14日后逐渐减至最小有效量。无效病例在以后2周停药。结果有效4例,血清肌肝减少70～90%,治疗 This article describes 10 cases of idiopathic acute glomerulonephritis patients, both proteinuria, hematuria and urinary sediment erythrocyte tubular, progressive loss of renal function, and renal biopsy more than 60% of glomerular epithelial cells crescent. After a more comprehensive examination and has ruled out can cause crescent glomerulonephritis all diseases. Methylprednisolone 1g / 24h intravenous “shock” on the 7th, then switch to oral prednisone, start 80mg / day, reduced to 60mg / day after 7 days, gradually reduced to the minimum effective dose after 14 days. Invalid cases were discontinued two weeks later. The results were effective in 4 cases, 70% -90% reduction in serum muscle liver, treatment