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目的探讨立体定向靶向微创手术应用于脑胶质瘤的临床治疗效果。方法 40例脑胶质瘤患者,根据治疗方法不同分为对照组和观察组,各20例。对照组采用常规开颅肿瘤切除术进行治疗,观察组采用立体定向靶向微创手术进行治疗,观察分析两组患者的治疗效果及日常生活活动能力(ADL)评分、神经功能改善评分和2年内的存活率。结果观察组患者总有效率为95%,高于对照组的70%,差异有统计学意义(P<0.05)。观察组患者的ADL评分为(79.63±3.68)分,神经功能缺损程度评分量表(CSS)评分为(29.67±1.16)分,均优于对照组的(53.6±1.49)、(39.7±2.46)分,差异有统计学意义(P<0.05)。观察组患者2年内的存活率为80%,高于对照组的50%,差异有统计学意义(P<0.05)。结论采用立体定向靶向微创手术治疗脑胶质瘤可有效提高患者的治疗效果,改善自理能力和神经缺损程度,提高患者2年内的生存率,为胶质瘤患者的治疗提供较为科学的临床价值,值得临床信采纳。
Objective To investigate the clinical effect of stereotactic targeted minimally invasive surgery in glioma. Methods Forty cases of glioma patients were divided into control group and observation group according to different treatment methods, 20 cases in each group. The control group was treated by conventional craniotomy. The observation group was treated with stereotactic targeted minimally invasive surgery. The therapeutic effect, ADL score, improvement of neurological function score, Survival rate. Results The total effective rate in observation group was 95%, which was higher than that in control group (70%), the difference was statistically significant (P <0.05). The ADL score of the observation group was (79.63 ± 3.68) points and the CSS score was (29.67 ± 1.16) points, which were all better than those of the control group (53.6 ± 1.49) and (39.7 ± 2.46) Points, the difference was statistically significant (P <0.05). The 2-year survival rate in observation group was 80%, which was higher than that in control group (P <0.05). Conclusion Stereotactic targeted minimally invasive surgery for glioma can effectively improve the therapeutic effect of patients, improve the ability of self-care and the degree of nerve defects, improve the survival rate of patients within 2 years, provide a more scientific clinical treatment for patients with glioma Value, worthy of clinical acceptance.