目的研究苦楝子Melia azedarach醇提物的化学成分。方法采用硅胶色谱技术进行分离纯化,根据理化性质和光谱学方法进行结构鉴定。结果分离得到9种化合物,分别鉴定为21α,25-二甲氧基苦楝酮二醇(1)、苦楝二醇(2)、2,3-二羟基-1-(4-羟基-3-甲氧基)苯基-1-酮(3)、松柏醛(4)、苦楝新醇(5)、(E)-3,3′-二甲氧基-4,4′-二羟基二苯乙烯(6)、5-羟甲基糠醛(7)、原儿茶醛(8)、芦丁(9)。结论化合物1、3、4、7～9系首次从该植物中分离得到。 Objective To study the chemical constituents of Melia azedarach alcohol extract. Methods Silica gel chromatography was used to separate and purify the compounds. The structures were identified by physicochemical properties and spectroscopic methods. Results Nine compounds were isolated and identified as 21α, 25-dimethoxyzonediol (1), nerolidin (2), 2,3-dihydroxy-1- (5), (E) -3,3’-dimethoxy-4,4’-dihydroxystilbene (6), 5-hydroxymethyl furfural (7), protocatechuic aldehyde (8) and rutin (9). Conclusion Compounds 1, 3, 4, 7-9 are isolated from this plant for the first time.