本文对1982—1984年在一冶医院出生的健康新生儿,健康低体重儿和早产儿计150例,根据孕期及体重不同分为四组进行出生后24小时内的卡介苗接种。结果:健康低体重儿和早产儿同健康新生儿相比,在卡介苗接种的局部反应上无明显不同,在接种后12周结素试验阳转率,阳转均经等方面,差异均无显著性意义,且无一例发生严重副反应。 In this paper, 150 cases of healthy newborns, healthy low birth weight infants and premature infants born in a hospital in 1982-1984 were divided into four groups according to their pregnancy and body weight. BCG vaccination within 24 hours after birth. Results: Compared with healthy newborns, there was no significant difference in the local response of BCG vaccination among healthy low birth weight infants and premature infants. There was no significant difference in the positive rate of positive tuberculin test after 12 weeks of inoculation , And no serious side effects occurred.