论文部分内容阅读
目的:探讨血浆N端脑钠肽前体(NT-pro BNP)在重症社区获得性肺炎(SCAP)患者撤机中的预测价值。方法:将应用气管插管机械通气治疗的SCAP患者选择123例根据拔管后48 h内无需复插或通气支持分为成功组(n=87)和失败组(n=36),比较两组患者在气管插管机械通气时、拟撤机时血浆NT-pro BNP浓度及其差值。结果:与失败组相比,成功组气管插管机械通气时、拟撤机时血浆NT-pro BNP浓度均明显降低,分别为[1694(1392,2534)vs 2520(1976,2942),P<0.05;468(391,882)vs 909(708,1279),P<0.O5],但差值明显高于失败组[1360(746,1731)vs 502(281,642),P<0.O5]。结论:监测NT-pro BNP对SCAP患者的撤离呼吸机有较好的预测作用。
Objective: To investigate the predictive value of plasma N-terminal proBNP (NT-pro BNP) in patients with severe community-acquired pneumonia (SCAP). Methods: A total of 123 patients with SCAP who were treated with endotracheal intubation and mechanical ventilation were divided into two groups according to extubation group (n = 87) and failure group (n = 36) Patients in the endotracheal intubation mechanical ventilation, the proposed weaning when plasma NT-pro BNP concentrations and their differences. Results: Compared with the failed group, the plasma concentrations of NT-pro BNP in the successful group were significantly decreased at mechanical ventilation of the tracheal intubation group (1694 (1392, 2534) vs 2520 (1976, 2942), P < 0.05; 468 (391,882) vs 909 (708,1279), P <.O5], but the difference was significantly higher than the failure group [1360 (746,1731) vs 502 (281,642), P <0.O5]. CONCLUSIONS: Monitoring NT-pro BNP is a good predictor of withdrawal ventilator in patients with SCAP.