目前,国内尚无公认的慢性难治性血小板减少性紫癜(Refractory Idiopathic Throm bocytopenic Purpura,RITP)的定义。有学者认为,由于脾脏切除术是迄今为止治疗特发性血小板减少性紫癜(ITP)最有效和疗效最持久的治疗措施,因此,如果患者没有接受脾切除术,一般不将其归为RITP~[1]。但基于当前我国较少实施脾脏切除术之现状,加之美罗华等一些行之有 At present, there is no recognized definition of chronic refractory thrombocytopenic purpura (Refractory Idiopathic Thromobocytopenic Purpura, RITP). Some scholars believe that, because splenectomy is by far the treatment of idiopathic thrombocytopenic purpura (ITP) the most effective and the most durable therapeutic measures, therefore, if the patient did not accept splenectomy, generally not be classified as RITP ~ [1]. However, based on the current status of our country less implementation of splenectomy, combined with the United States and some other rover