Syntheses,Crystal Structures and Antibacterial Activities of Schiff Base of Nickel(Ⅱ) and Copper(Ⅱ)

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A new kind of Schiff base HL(HL= 1-phenyl-3-methyl-4-(p-methylbenzoyl)-5-pyrazolone with L-Leucine methyl ester) and complexes Ni L′_2·0.75C_2H_5OH·0.25H_2O,Cu L′′2(L′ = 1-phenyl-3-methyl-4-(p-methylbenzoyl)-5-pyrazolone with L-leucine ethyl,L′′ = 1-phenyl-3-methyl-4-(p-methylbenzoyl)-5-pyrazolone with L-leucine) have been synthesized and structurally determined by X-ray diffraction. For HL: crystal structure determination indicates that there are two independent HLs with different conformations in one asymmetric unit. For complex 1: the Ni(Ⅱ) ion is six-coordinated by two carbonyl oxygen atoms from pyrazolone ring,two nitrogen atoms from different HL′ and two oxygen atoms from L-Leucine ethyl ester to form a distorted octahedral geometry. For complex 2: the Cu(Ⅱ) ion is four-coordinated by one carbonyl oxygen atom from the pyrazolone ring,one nitrogen atom from HL′′,and two different carboxylic oxygen atoms from L-leucine with the same conformation to form a distorted quadrilateral geometry. A new kind of Schiff base HL (HL = 1-phenyl-3-methyl-4- (p-methylbenzoyl) -5-pyrazolone with L-Leucine methyl ester) and complexes Ni L’_2 · 0.75C_2H_5OH · 0.25H_2O, Cu L ’= 1 -phenyl-3-methyl-4- (p-methylbenzoyl) -5-pyrazolone with L-leucine ethyl, methylbenzoyl) -5-pyrazolone with L-leucine) have been synthesized and structurally determined by X-ray diffraction. For HL: crystal structure determination that there are two independent HLs with different conformations in one asymmetric unit. For complex 1: the Ni (II) ion is six-coordinated by two carbonyl oxygen atoms from pyrazolone ring, two nitrogen atoms from different HL ’and two oxygen atoms from L-Leucine ethyl ester to form a distorted octahedral geometry. For complex 2: the Cu (II) ion is four-coordinated by one carbonyl oxygen atom from the pyrazolone ring, one nitrogen atom from HL ", and two different carboxylic oxygen atoms from L-leucine with the same conformation to form a di storted quadrilateral geometry.
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