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目的:分析婴幼儿朗格汉斯细胞组织细胞增生症(LCH)侵犯肝脏的影像学表现特点,提高诊断能力。方法:11例经临床、病理证实的LCH患者纳入回顾性分析,男9例,女2例,平均年龄17个月,全部完成腹部CT增强检查,3例完成MRI检查。结果:肝脏弥漫增大,CT上肝内病灶呈低密度,无明显强化,MRI上呈长T1长T2信号;病灶形态和分布可分为三种类型:①中央型,沿中央门脉两侧分布的双线条状病变,7例;②周围型,肝实质内多发结节,2例;③弥漫型,同时有中央和周围分布的病灶,2例。伴有胆管扩张3例、肠壁增厚5例、腹腔积液1例、脾肿大9例、淋巴结肿大3例。结论:婴幼儿LCH肝脏侵犯影像表现有特点,有助于诊断和临床处理。
OBJECTIVE: To analyze the imaging features of liver in children with Langerhans cell histiocytosis (LCH) and to improve the diagnostic ability. Methods: Eleven patients with clinically and pathologically confirmed LCH were enrolled in this retrospective analysis. There were 9 males and 2 females with an average age of 17 months. All of them completed CT enhanced examination of abdomen and 3 completed MRI examination. Results: The liver was diffusely enlarged, and the lesion in the liver showed low density and no significant enhancement on CT. The long T1 long T2 signal was observed on the MRI. The morphology and distribution of the lesion can be divided into three types: ① central type, Distributed in the double line lesions, 7 cases; ② peripheral type, multiple nodules within the liver parenchyma, 2 cases; ③ diffuse type, with central and peripheral distribution of lesions, in 2 cases. With bile duct dilatation in 3 cases, 5 cases of intestinal wall thickening, 1 case of ascites, splenomegaly in 9 cases, 3 cases of lymphadenopathy. Conclusion: The characteristics of LCH liver invasion in infants and young children are characterized by images, which are helpful for diagnosis and clinical treatment.