目的:单采血小板浓缩物(PC)中混杂的白细胞(WBC),输注后可引起一系列不良反应。为获得含WBC较低的PCs,最近引入一种新的“流体粒子床”技术白细胞减少系统(LRS)。方法:作者前瞻性检测了LRS单采对供者、PCs产品的质量(n=120)以及相应受者血小板数增加的影响。常规制备的单采PCs作为对照组(n=2)。用流式血细胞计数检测血小板糖蛋白。结果:作者未发现LRS单采对供者有严重不良反应,只是供血后淋巴细胞计数绝对值由1,787±505/μl降至1,405±383/μl(P< OBJECTIVE: Mixed white blood cells (WBCs) in apheresis concentrate (PC) can cause a series of adverse reactions after infusion. To obtain PCs with lower WBCs, a new “fluid particle bed” technology leukopenia (LRS) has recently been introduced. METHODS: We prospectively examined the impact of LRS apheresis on donor and PC product quality (n = 120) and the corresponding increase in platelet count. Conventionally prepared apheresis PCs were used as a control (n = 2). Platelet glycoprotein was detected by flow cytometry. RESULTS: The authors found no serious adverse reactions to LRS with donor apheresis, except that the absolute value of lymphocyte count decreased from 1,787 ± 505 / μl to 1,405 ± 383 / μl (P <