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目的探讨颅鼻沟通性肿瘤的外科治疗。方法回顾性分析四川大学华西医院神经外科2005年6月至2007年6月手术治疗的18例颅鼻沟通性肿瘤。结果本组18例均行开颅联合鼻内窥镜手术,一期手术切除肿瘤并行颅底重建。手术全切14例,次全切除4例,术后发生一过性脑脊液漏2例,18例患者均恢复良好,本组无手术死亡病例。随访5月~2年半,4例复发,3例失访,其余11例存活良好。结论显微神经外科联合鼻内窥镜技术一期手术治疗颅鼻沟通性肿瘤,可以较安全彻底地切除肿瘤并稳妥地进行颅底重建,手术全切率高,并发症率低。
Objective To investigate the surgical treatment of cranial and nasal tumors. Methods Retrospective analysis of 18 cases of craniocervical tumors in Department of Neurosurgery, West China Hospital, Sichuan University from June 2005 to June 2007. Results The group of 18 patients underwent craniotomy combined with endoscopic sinus surgery, a surgical resection of the skull base reconstruction. There were 14 cases of complete resection, 4 cases of subtotal resection, 2 cases of transient cerebrospinal fluid leakage after surgery, and 18 cases recovered well. There was no surgical death in this group. Followed up for 5 months to 2 years and a half, 4 recurred, 3 lost follow-up, and the remaining 11 survived well. Conclusions Microsurgical neurosurgery combined with endoscopic sinus surgery in the treatment of cranial and nasal tumors can safely and thoroughly remove the tumor and perform the skull base reconstruction safely. The total surgical incision rate and the complication rate are low.