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目的：了解综合干预对精神分裂症患者认知功能的影响。方法将55例精神分裂症患者按照随机数字表法分为实验组25例，对照组30例，均予以常规抗精神病药物治疗及护理，实验组在此基础联合综合干预，观察住院全程。于治疗前后采用重复性成套神经心理状态测验评定患者的认知功能。结果治疗后实验组重复性成套神经心理状态测验总分及各因子分均较治疗前显著升高(P <0.05或0.01)，且显著高于对照组(P 0.05)。结论药物治疗联合综合干预能显著改善精神分裂症患者的认知功能，有利于提高患者的生活质量，优于单用药物治疗。“,”Objective To survey the influences of comprehensive intervention on schizophrenics’cognitive functions.Methods Fifty-five schizophrenics were assigned to experimental (n=25)and control group (n =30)according to random number table,both groups treated with routine an-tipsychotic treatment and nursing,on this basis experimental group was plus comprehensive intervention, and whole courses of hospitalization were observed.Cognitive functions were assessed with the Repeatable Battery for the Assessment of Neuropsychological Status (RBANS).Results After treatment the total and each factor score of the RBANS heightened more significantly compare with pretreatment in experi-mental group (P 0.05),and were sig-nificantly higher in experimental than in control group (P <0.05 ).Conclusion Pharmacotherapy plus comprehensive intervention could notably improve schizophrenics’cognitive function and is beneficial to the increase of their quality of life compared with single pharmacotherapy.