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由于抗生素在临床上广泛过度地使用,造成了多重耐药菌(multi-drug resistamt bacteria,MDR)迅速蔓延,对婴幼儿、免疫缺陷者和老年人的威胁极大。MDR引起的疾病常用的抗菌药物(多数β-内酰胺类、氨基糖苷类、喹诺酮类、大环内酯类等)治疗效果欠佳或无效,主要有:肺结核、肺炎、及其它呼吸道感染等,并伴有较高的病死率。在比利时,16家监护病房(ICU)进行耐药监测,发现产诱
The widespread use of antibiotics in the clinic has led to the rapid spread of multi-drug resistamt bacteria (MDR), which poses a significant threat to infants, immunocompromised persons and the elderly. Common diseases caused by MDR Antibiotics (most β-lactams, aminoglycosides, quinolones, macrolides, etc.) poor or ineffective treatment, mainly: tuberculosis, pneumonia, and other respiratory infections, Accompanied by a higher case fatality rate. In Belgium, 16 intensive care units (ICUs) were drug-resistant and found to be induced