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目的:探讨无口腔肿瘤手术及放疗史的患者n 18F－脱氧葡萄糖(FDG) PET/CT显像时舌部局灶性生理性摄取(FPU)的变异模式及特征。n 方法:回顾性分析2013年1月至2017年12月于山西医科大学第一医院行常规全身PET/CT显像的6 233例患者，排除有口腔肿瘤手术及放疗史的患者324例，纳入5 909例，其中男3 418例，女2 491例，年龄2～95(平均58)岁。部分患者进行了张口位状态下的局部PET/CT和诊断剂量CT检查。从FDG摄取增高部位和累及范围的角度分析舌部FPU变异模式及形态特征，并测量最大标准摄取值(SUVn max)。n 结果:常规PET/CT显像检出76例患者[男49例，女27例，年龄40～83(平均64)岁]的76个偶发舌部FPU经口腔医学检查及>6个月的随访确认，舌部FPU的发生率为1.29% (76/5 909)。76例患者中41例进行了张口位局部PET/CT和诊断剂量CT检查。舌部FPU变异模式可以归纳为3种类型：Ⅰ型，共68例(1.15%，68/5 909)，FDG摄取仅涉及中线处舌体前部(靠近舌尖部)，为“点状”摄取；Ⅱ型，共5例(0.08%，5/5 909)，FDG摄取主要涉及颏舌肌的中间部分，为“短条形”摄取；Ⅲ型，共3例(0.05%，3/5 909)，FDG摄取涉及舌体大部及颏舌肌，为“T形”摄取。Ⅰ型、Ⅱ型舌部FPU的SUVn max分别为5.53(4.53，7.30)、19.50(17.10，22.74)，3例Ⅲ型SUVn max分别为23.34、27.50和35.14。n 结论:在无口腔疾患手术及放疗史的患者中，舌部FPU有其特定模式和特征，张口位PET/CT显像有助于显示其详细特征。“,”Objective:To analyze variant patterns and characteristics of focal physiological uptake (FPU) in the tongue on n 18F-fluorodeoxyglucose (FDG) PET/CT imaging in patients without a history of oral tumor surgery and radiotherapy.n Methods:A total of 6 233 consecutive patients who underwent routine whole-body PET/CT scan between January 2013 and December 2017 in the First Hospital of Shanxi Medical University were investigated retrospectively, and 324 patients with a history of oral surgery and radiotherapy were excluded, the remaining 5 909 patients (3 418 males, 2 491 females, age range: 2-95 (average: 58) years) were enrolled. A part of the patients underwent local PET/CT scan and CT scan with diagnostic dose, covering the oral cavity on mouth-opening position. The morphological characteristics of FPU patterns were analyzed, and the maximum standardized uptake value (SUVn max) was measured.n Results:Seventy-six FPUs in 76 patients (49 males, 27 females, age range: 40-83 (average 64) years) identified by routine whole-body PET/CT scan were confirmed by clinical examination from a specialist in stomatology or follow-up for more than 6 months. Forty-one of the 76 patients subsequently underwent local PET/CT scan and diagnostic CT scan on mouth-opening position. The incidence of FPU in the tongue was 1.29%(76/5 909). The FPU patterns could be classified into three types: type Ⅰ with FDG uptake involved only anterior part of the tongue body in the midline (near the tip of the tongue), which showed as a “ dotted” shape( n n=68; 1.15%, 68/5 909); type Ⅱ with FDG uptake involved mainly middle part of the genioglossus muscle, which showed as a “ bar-shorted” shape ( n n=5; 0.08%, 5/5 909); type Ⅲ with FDG uptake involved large part of the tongue body and the genioglossus, which showed as a “ T” shape( n n=3; 0.05%, 3/5 909). The SUVn max in patients with type Ⅰ and type Ⅱ were 5.53(4.53, 7.30), 19.50(17.10, 22.74) respectively. The SUVn max in 3 patients with type Ⅲ were 23.34, 27.50 and 35.14, respectively.n Conclusion:In patients without a history of oral tumor surgery and radiotherapy, the FPU in the tongue has its specific pattern, and PET/CT scan on mouth-opening position helps to reveal the detailed features.