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研究了Ｎ－异丙基丙烯酰胺（ＮＩＰＡＡｍ）在水溶液及四氢呋喃溶液中的辐射聚合及它与活性有机单体Ｎ－丙烯酰氧基丁二酰亚胺（ＮＡＳＩ）辐射共聚，以制备水溶性、温度敏感性均聚物及共聚物。结果表明，室温、无氧条件下在水或ＰＢＳ缓冲溶液中ＮＩＰＡＡｍ及它与ＮＡＳＩ共聚物（ｐｏｌｙＮＩＰＡＡＭ－ＮＡＳＩ）辐射合成的最佳条件为：剂量１－７ｋＧｙ，剂量率不小于４０Ｇｙ／ｍｉｎ，溶液中单体浓度小于１％。单体在四氢呋喃中辐射聚合可得到粉末状固体聚合物。将这种聚合物溶于水中仍具有温度敏感性，用此法可获得较多的此类聚合物，只是分子量偏低（Ｍｎ只有１０４数量级），其合成条件与在水溶液中也有较大差异。该聚合物经热性质测定表明，多次溶解、沉淀后仍能保持其热性质的均一性和稳定性。
The radiation polymerization of N-isopropylacrylamide (NIPAAm) in aqueous solution and tetrahydrofuran solution and its radiation copolymerization with N-acryloyloxy succinimide (NASI) as the active organic monomer were studied to prepare water-soluble, Temperature-sensitive homopolymers and copolymers. The results showed that the optimal conditions for the synthesis of NIPAAm and its polyNIPAAM-NASI radiation in water or PBS buffer solution at room temperature and in anaerobic conditions were 1-7kGy dose rate of not less than 40Gy / min, solution In the monomer concentration of less than 1%. Radiation polymerization of the monomers in tetrahydrofuran gives powdered solid polymers. The polymer is still water-soluble temperature-sensitive, with this method can be more such polymers, but the molecular weight is low (Mn only 104 orders of magnitude), the synthesis conditions and in aqueous solution are also quite different. The thermal properties of the polymer showed that after repeated dissolution and precipitation, the thermal uniformity and stability of the polymer remained unchanged.