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目的探讨功能性消化不良(FD)的临床特征并进行针对性治疗。方法对我院消化科2001年1月至2005年12月诊断为FD的81例患者进行回顾性分析。将其分为制酸药组、促动力药组、联合用药组、以及对照组进行治疗观察。结果81例中动力不良型(DD)38例,占46.9%;溃疡型(UD)29例,占35.8%;非特异型(ND)14例,占17.3%。75例Hp检测者,阳性20例,阳性率26.67%。制酸药、促动力药或两类药物联合应用有效率分别为80.95%、85.00%和90.00%,与对照组比较P<0.01。结论FD的亚型以动力不良型为最常见,Hp感染率与正常人群无差别,制酸药、促动力药治疗有效。
Objective To investigate the clinical features of functional dyspepsia (FD) and to conduct targeted therapy. Methods A retrospective analysis was performed on 81 patients diagnosed as FD from January 2001 to December 2005 in our hospital. They were divided into antacid group, motility group, combination group, and control group for treatment. Results Among the 81 cases, 38 cases were moderate dysmotility (DD), accounting for 46.9%; 29 cases were ulcer (UD), accounting for 35.8%; and 14 cases were nonspecific (ND), accounting for 17.3%. 75 cases of Hp test, positive in 20 cases, the positive rate of 26.67%. The effective rates of antacids, propofol or combination of two drugs were 80.95%, 85.00% and 90.00% respectively, P <0.01 compared with the control group. Conclusions The subtypes of FD are the most common cases with poor power, and the infection rate of Hp is not different from that of the normal population. The antacids and motility drugs are effective.