论文部分内容阅读
目的评价地塞米松对母乳性黄疸综合征的疗效,探讨母乳性黄疸综合征与胆汁淤积的关系,并调查停喂母乳对母婴的身心影响。方法将符合诊断标准的93例患儿分为A,B,C 3组。A组应用小剂量地塞米松,停喂母乳;B组应用小剂量地塞米松,不停喂母乳;C组停喂母乳,期间不用任何药物。3组治疗时间均为3 d,治疗过程中经皮测定胆红素值,并调查喂养方式对母婴身心健康的影响。结果 3组患儿皮肤黄疸均有不同程度的减轻,在黄疸消退时间及减轻程度上,A组,B组优于C组,A组B组差异无统计学意义。结论胆汁淤积可能为母乳性黄疸综合征病理机制之一,小剂量地塞米松治疗晚发性母乳性黄疸疗效确切,暂停母乳喂养对母婴均有不同程度的身心影响。
Objective To evaluate the curative effect of dexamethasone on breast milk jaundice syndrome and to explore the relationship between breast milk jaundice syndrome and cholestasis and investigate the effect of stopping breastfeeding on mother and infant. Methods Ninety-three children who met the diagnostic criteria were divided into A, B and C groups. Group A was given low-dose dexamethasone and stopped breast-feeding; Group B was given low-dose dexamethasone and kept breast-feeding; Group C stopped breast-feeding without any medication. The treatment time was 3 days in each group. The bilirubin value was measured by percutaneous method during the course of treatment, and the effect of feeding mode on maternal and child physical and mental health was also investigated. Results The skin jaundice in all three groups were relieved to varying degrees. There was no significant difference in the time and extent of jaundice subsidence in group A and group B compared with group C, and in group A and group B. Conclusion Cholestasis may be one of the pathological mechanisms of breast milk jaundice syndrome. Low-dose dexamethasone is effective in treating late-onset breast milk jaundice. Suspending breastfeeding has different effects on both mother and child.