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目的观察培他尼治疗慢性阻塞性肺病(COPD)的疗效。方法慢性阻塞性肺病80例入选者随机分组,对照组38例采用常规综合治疗,治疗组42例在常规治疗基础上加用培美他尼24mg静脉滴注,每天1次,共14天。治疗前后根据临床表现及动脉血气分析、肺功能进行综合评定。结果治疗组病情改善有效率88.1%,对照组63.2%。治疗组各指标在治疗后较对照组改善率更显著。结论在COPD治疗中加用培美他尼能改善病情,改善肺功能,提高患者生活质量。
Objective To observe the efficacy of pertitani in the treatment of chronic obstructive pulmonary disease (COPD). Methods Eighty patients with chronic obstructive pulmonary disease (COPD) were randomly divided into control group (n = 38) and control group (n = 38). Conventional treatment was given to 42 patients in the treatment group. Pemetrexed 24mg was given intravenously once a day for 14 days. Before and after treatment according to clinical manifestations and arterial blood gas analysis, lung function comprehensive assessment. Results The treatment group improved the effective rate 88.1%, control group 63.2%. The treatment group than in the control group after treatment indicators of improvement was more significant. Conclusions Pemetretam can improve the condition, improve pulmonary function and improve the quality of life in patients with COPD.