生霉素治疗细菌性痢疾52例疗效观察

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生霉素是一种广谱抗菌素,是苏联出品的金霉素制剂,在儿科方面用途极广。我们曾应用生霉素治疗102例小儿肺炎及52例细菌性痢疾,疗效尚佳,很少发生不良反应。临床资料病例情况:52例中男性35例,女性17例。年龄1月以下4例,1至6月13例,6月至1岁19例,1岁至2岁10例,2至3岁6例。急性患儿(病程不到2月)44例,慢性患儿(病程超过2月)8例。患儿均有典型痢疾病史和大便化验,只有10例作了大便培养,内6例阳性:志贺氏2例,弗氏3例,宋内氏1例。发热在38度摄氏以上者22例。过去用药物情况:52例患儿中38侧曾使用其他药物,三天后无效时才改用生霉素。38例中用过氯霉素或合霉素者19例、氯霉素合并链霉素者12例、氯霉素合并磺胺胍者7例。 Coatomycin is a broad-spectrum antibiotic, which is a chlortetracycline preparation produced by the Soviet Union and has a very wide range of uses in pediatrics. We have applied biocidal treatment of 102 cases of children with pneumonia and bacterial diarrhea in 52 cases, the effect is good, with minimal adverse reactions. Clinical data Case: 52 cases of 35 males and 17 females. There were 4 cases from January to June, 13 from January to June, 19 cases from June to 1 year old, 10 cases from 1 year to 2 years old and 6 cases from 2 to 3 years old. 44 cases of acute children (duration less than 2 months), chronic children (duration of more than 2 months) in 8 cases. There was a history of typical dysentery in children and stool tests, only 10 cases were stool culture, 6 cases were positive: Shiga 2 cases, Freund’s 3 cases, Song Nei’s 1 case. 22 cases of fever over 38 degrees Celsius. In the past the use of drugs: 52 cases of children in the 38 side had used other drugs, three days after the change to the use of non-viable antibiotics. Among the 38 patients, 19 were chloramphenicol or tobramycin, 12 were chloramphenicol with streptomycin, and 7 were chloramphenicol with sulfonamides.
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