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目的综合评价德宏州实施强化免疫项目16年消灭脊髓灰质炎的防治效果。方法采用脊髓灰质炎减毒活疫苗糖丸,对相对人群在基础免疫的基础上实施强化免疫;建立敏感的AFP监测系统,监测AFP病例;统计分析防治措施及效果。结果1993～2008年全州儿童基础免疫应服脊灰疫苗228578人次,实服苗216236人次,服苗率94.6%;强化和扫荡免疫登记儿童2059725人次,实服苗儿童1970553人次,服苗率95.67%,接种流动儿童128617人次,其中零剂次儿童38868人次;监测发现AFP175例,年均发病率1.15/10万,合格粪便标本采集率93.14%,送检率94.29%,检验结果均为非脊灰病例,1990年后未发生脊灰病例。结论德宏州实施脊灰强化免疫策略后,在相对人群中建立了牢固的免疫屏障,AFP监测系统敏感,连续十九年保持了无脊灰状态,达到了项目的预期效果。
Objective To comprehensively evaluate the prevention and control of poliomyelitis eradication in 16 years in Dehong Prefecture. Methods The live attenuated poliomyelitis vaccine was administered to the relative population on the basis of the basic immunization. A sensitive AFP monitoring system was established to monitor the AFP cases. Statistical analysis of the prevention and control measures and their effects was also made. Results In the period of 1993-2008, there were 228578 polio vaccines in Guangzhou and 2216236 in Fuzhou, 94.6% of the women served the vaccine; 2059725 children were enrolled in intensive care and mop-up vaccination; %, And the number of floating children vaccinated was 126,617, of which 38,868 were zero-dose children. AFP was found in 175 cases with an average annual incidence rate of 1.15 / 100,000. The sampling rate of qualified stool samples was 93.14% and the detection rate was 94.29% Gray cases, polio cases did not occur after 1990. Conclusions After implementing the strategy of polio-enhanced immunization in Dehong Prefecture, a solid immune barrier was established in the relative population. The AFP monitoring system was sensitive and maintained its polio-free status for 19 consecutive years, thus achieving the expected results of the project.