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疟疾病人贫血的发生机制尚不清楚。动物模型研究显示反应性氧介质 (ＲＯＩ)参与了疟原虫的破坏和疟疾病理学过程。为研究ＲＯＩ在人疟疾中的作用 ,作者对加蓬Ｌａｍｂａｒ啨ｎ啨Ａｌｂｅｒｔ Ｓｃｈｗｅｉｔｚｅｒ医院 1 0 0例严重镰状疟原虫疟疾儿童的ＲＯＩ水平进行了测定。
The pathogenesis of anemia in malaria patients is not clear. Animal model studies have shown that reactive oxygen mediators (ROIs) are involved in the destruction of malaria parasites and malaria pathology. To investigate the role of ROI in human malaria, the authors measured the ROI level of 100 severe malaria cases of Plasmodium falciparum in the Lamborghini Albert Schweitzer hospital in Gabon.