目前,由于抗生素在临床的广泛应用,耳中毒的发生率逐年增高,给患者造成极大的痛苦,已成为主要致聋的原因之一,并直接影响儿童的学习及成人的工作、生产。本刊特请有关专家,就抗生素所致耳中毒的发生原因、发病机制及如何预防与治疗等,进行专题论述。希望广大临床工作者能了解这一问题的严重性,掌握合理用药方法,预防耳中毒的发生。 Currently, due to the wide application of antibiotics in clinic, the incidence of ototoxicity increases year by year, causing great suffering to patients. It has become one of the major causes of deafness and has a direct impact on children’s learning and adult work and production. This journal especially invited relevant experts to discuss the causes, pathogenesis and prevention and treatment of ototoxicity caused by antibiotics. Hope that the majority of clinical workers can understand the seriousness of this problem, to master the rational use of drugs to prevent the occurrence of ototoxicity.