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采用济南军区青岛第一疗养院研制的硝酸甘油气雾剂治疗冠心病心绞痛36例,并设对照组19例,对其临床治疗效果进行了对比观察。结果发现心绞痛的缓解时间:治疗组的起效时间为40～60s,对照组是2～5min,治疗组较对照组明显缩短;治疗组心电图的有效改变明显高于对照组。该药有头晕、头痛、恶心等副作用。提示硝酸甘油气雾剂可做为治疗冠心病心绞痛的首选药。
36 cases of angina pectoris of coronary heart disease were treated with nitroglycerin aerosol developed by Qingdao First Infirmation Institute of Jinan Military Region and 19 cases of control group. The clinical therapeutic effect was compared. The results showed that the relief time of angina pectoris was 40-60s in the treatment group and 2-5min in the control group, which was significantly shorter in the treatment group than in the control group. The effective changes of electrocardiogram in the treatment group were significantly higher than those in the control group. The drug has dizziness, headache, nausea and other side effects. Prompt nitroglycerin aerosol can be used as the preferred drug for the treatment of angina pectoris.