论文部分内容阅读
为了评价叶绿素衍生物光动力疗法预防膀胱癌术后复发的疗效,将60例膀胱癌术后患者随机分成两组,分别采用叶绿素衍生物光动力疗法(C组)和噻替哌膀胱内灌注(T组)。结果显示:C组中Ⅰ级与Ⅱ、Ⅲ级肿瘤复发率(分别为0％、66.7％)比较有显著性差异(P<0.01);T组中T_1、T_2期肿瘤与T_3期肿瘤复发串(分别为20.o％、31.1％和71.4％)的比较、单发与多发肿瘤复发率(分别为25.0％、58.3％)的比较均有显著性差异(均P<0.01),但组间各项比较均无明显差异。这一结果提示,叶绿素衍生物光动力疗法和噻替哌膀胱内灌注在预防肿瘤术后复发方面有相似疗效,而副作用前者明显较后者轻微。
In order to evaluate the efficacy of chlorophyll derivative photodynamic therapy in the prevention of postoperative recurrence of bladder cancer, 60 cases of postoperative bladder cancer were randomly divided into two groups, which were treated with chlorophyll derivative photodynamic therapy (group C) T group). The results showed that there was a significant difference in the recurrence rates of grade Ⅰ, Ⅱ and Ⅲ in group C (0%, 66.7%, respectively) (P <0.01); in group T, the recurrence of T_1 and T_2 (Respectively 20.0%, 31.1% and 71.4%). The recurrence rates of single and multiple tumors (25.0% and 58.3%, respectively) were significantly different (all P <0.01) There is no significant difference between the various comparisons. This result suggests that chlorophyll derivative photodynamic therapy and thioipetidol intravesical instillation in the prevention of tumor recurrence has a similar effect, while the former was significantly less side effects than the latter.