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液体或食物入胃后,胃的舒张反应称胃适应性舒张。作者在豚鼠游离胃做了如下实验:(1)逐步升高与胃相通的灌流液贮瓶的高度以加大胃内压力,胃发生适应性舒张;用河豚毒素温育胃,其适应性舒张反应消失,说明此反应为神经源性的,但用胍乙啶和阿托品抑制肾上腺素能和胆碱能神经,不能抑制此压力舒张反应。说明本反应是非肾上腺素能非胆碱能神经参与的;(2)NO合成的抑制剂对胃舒张反应的作用:用N~G-monomethyl-L-arginiee(MeArg)或N~w-nitro-L-arginine methyl ester(NO_2Arg)温育胃后,压力诱
After the liquid or food into the stomach, the gastric vasodilation is called gastric adaptive relaxation. The authors made the following experiments on the free stomach of guinea pigs: (1) Gradually increase the height of the perfusion fluid storage bottle communicating with the stomach to increase gastric pressure and adaptive relaxation of the stomach; teatotoxin to heat the stomach and its adaptive relaxation The reaction disappeared, indicating that this reaction is neurogenic, but with guanethidine and atropine inhibition of adrenergic and cholinergic nerve, can not inhibit this pressure-relaxation response. (2) The effect of inhibitor of NO synthesis on gastric vasodilatation: N-G-monomethyl-L-arginiee (MeArg) or N-w-nitro- L-arginine methyl ester (NO 2 Arg) After incubation of the stomach, pressure induced