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目的:分析小剂量性激素补佳乐对于更年期综合征的疗效。方法:将58例更年期综合征患者根据用药方案,分为观察组(30例,口服戊酸雌二醇片)和对照组(28例,口服炔雌醇片),对比两组的更年期症状改善情况、用药安全性。结果:用药前,两组Kupperman评分值无差异统计意义(P>0.05);用药一疗程后,观察组Kupperman评分值明显低于对照组(P<0.05),另在用药期间,与对照组相比,观察组不良反应率也更低(P<0.05)。结论:小剂量戊酸雌二醇片对更年期综合征的疗效确切、用药安全性高。
OBJECTIVE: To analyze the efficacy of low-dose sex hormones for improving menopause syndrome. Methods: 58 cases of climacteric syndrome patients were divided into observation group (30 cases, oral estradiol valerate tablets) and control group (28 cases, oral ethinylestradiol tablets) according to the medication regimen. The improvement of menopausal symptoms was compared between the two groups Situation, medication safety. Results: Before treatment, Kupperman scores of the two groups showed no statistical significance (P> 0.05). After one course of treatment, the Kupperman score of the observation group was significantly lower than that of the control group (P <0.05) The rate of adverse reactions in the observation group was also lower (P <0.05). Conclusion: Low-dose estradiol valerate tablets are effective in treating climacteric syndrome with high safety.