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目的观察乳腺癌患者围手术期护理干预的临床效果。方法160例行乳腺癌根治术的乳腺恶性肿瘤患者，按照随机数字表法分为研究组和对照组，分别给予护理干预措施和常规护理措施，比较两组护理效果。结果研究组0级和I级患者所占的比例明显高于I 级和I I级，与对照组组间比较差异显著（P＜0.05）。结论围手术期的护理干预能调整手术后的乳腺癌患者的情绪。“,” Objective: To study the patients with breast cancer after the perioperative nursing clinical effect. Methods: 160 cases of breast malignant tumor patients were treated for breast cancer radical, according to random number table method is divided into research group and the control group, were given nursing intervention measures and conventional nursing measures, compared two groups of nursing effect. Results: Research group of grade 0 and grade I the proportion of patients was significantly higher than that of I and I I, significant differences between the control group and the group (P﹤0.05). Conclusion: The Perioperative nursing intervention can adjust the mood of the breast cancer patients after the surgery.