重点报道了以（１Ｒ，２Ｓ）或（１Ｓ，２Ｒ）－１，２－二苯基－２－氨基乙醇衍生物手性配体的合成及其用于不对称催化反应的研究，如去氢氨基酸的氢化、醛的乙基锌加成、酮的还原、活泼亚甲基化合物的烷基化、醛的硅腈化和瑞福马斯基反应等．研究了手性配体的结构、底物和反应条件等对上述反应的对映选择性和催化活性的影响． The synthesis of chiral ligands with (1R, 2S) or (1S, 2R) -1,2-diphenyl-2-aminoethanol derivatives and their applications in asymmetric catalysis have been reported, Hydrogenation of amino acids, addition of ethylzinc of aldehydes, reduction of ketones, alkylation of active methylene compounds, silanolylation of aldehydes and Rephabisch reactions. The effects of the structure, substrate and reaction conditions of the chiral ligand on the enantioselectivity and catalytic activity of the above reaction were studied.