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产羔数是现代养羊生产中最重要的经济性状之一,显著影响绵羊饲养的经济效益。绵羊产羔数属低遗传力(0.03~0.1)性状,常规育种方法遗传改良进展缓慢。随着现代分子生物技术的发展,产羔数相关分子标记已在绵羊生产中广泛应用,为提高绵羊繁殖力取得了一定成绩。此综述详述了绵羊产羔数相关主效基因如Fec B、BMP15、GDF9及IGF1、ESR、Ki SS1等候选基因的研究进展及应用,旨在为我国绵羊产羔数性状的遗传改良和培育我国特有的高繁殖力肉用绵羊新品种(系)提供科学依据。
The litter size is one of the most important economic traits in the modern sheep production and significantly affects the economic benefits of sheep breeding. Sheep lambing is a low heritability (0.03 ~ 0.1) traits, genetic improvement of conventional breeding methods slow progress. With the development of modern molecular biotechnology, the number of lambs related to molecular markers have been widely used in sheep production, in order to improve sheep fecundity and achieved some results. This review summarizes the research progress and application of major genes related to lambing in sheep such as Fec B, BMP15, GDF9, IGF1, ESR, Ki SS1 and other candidate genes, aiming at genetic improvement and breeding of litter size in sheep China’s unique high fecundity sheep with new varieties (lines) to provide a scientific basis.