氨基甲酸乙酯(EC)广泛存在于发酵食品、饮料和某些加热的含有乙醇的非发酵食品中。EC是一种水溶性致癌物,能诱发实验动物的肺、肝、甲状腺、皮肤及乳腺产生肿瘤。实验用断乳雄性C3H小鼠分为15组,每组18～21只。采用自来水、12％乙醇、市售的Concord白酒和红酒、雷司令白酒(酒中乙醇含量调至12％)作为小鼠饮料。将EC加入到上述饮料中,使小鼠每日摄入0,10和20 mg/kg体重EC。实验结果表明(1)饲养41周后,每日摄入20mg/kg体重EC饮水组的小鼠,其死亡率较其它组高(P<0.05),但摄入同等剂量EC饮用Concord白酒组的小鼠无一例死亡;(2)摄入EC的患瘤小鼠中肝细胞腺瘤数,饮酒组比 Urethane (EC) is widely found in fermented foods, beverages, and some heated non-fermented foods containing ethanol. EC is a water-soluble carcinogen that induces tumors in the lungs, liver, thyroid, skin and breast of experimental animals. Experimental weaned male C3H mice were divided into 15 groups of 18-21 each. Using tap water, 12% ethanol, commercially available Concord white wine and red wine, Riesling liquor (ethanol content adjusted to 12%) as a mouse drink. EC was added to the above beverages to induce daily intake of EC at 0, 10 and 20 mg / kg body weight. The results showed that: (1) After 41 weeks of feeding, the mortality of mice in EC drinking group with daily intake of 20mg / kg body weight was higher than that of other groups (P <0.05) None of the mice died; (2) The number of hepatocellular adenoma, the alcohol consumption group