徐××，男，11岁。因自幼视力差、听力欠佳、生长缓慢，上学后学习极差而就诊。既往无眼疾史，否认氨基糖式类抗菌素用药史及药物过敏史。孩患儿系母亲眼用短效避孕药期间受孕。孕期母亲曾反复“感冒发热”。患儿乳牙5～6岁才萌齐。前由5岁闭合。其父母非近亲婚配，身体健康。 Xu × ×, male, 11 years old. Due to poor vision since childhood, poor hearing, slow growth, poor learning and school attendance. Past history without eye disease, denied aminoglycoside antibiotic medication history and drug allergy history. Children with children during pregnancy ophthalmic short-acting contraceptives. Pregnant mothers have repeatedly “cold fever.” Baby teeth 5 to 6 years old children Meng Qi. Closed before the age of 5. Their parents are not close relatives, good health.