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目的通过白光模式、富士能智能染色内镜(FICE)、卢戈染色方法及在FICE模式下联合卢戈染色对食管病变进行内镜观察,比较不同模式诊断早期食管癌及癌前病变的临床应用价值。方法选取2015-2016年来医院内镜中心进行胃镜检查发现食管部位存在病变并取活检的患者393例,根据检查方法分为普通白光模式组(A组)97例、高清智能染色内镜组(B组)97例、卢戈染色组(C组)96例和高清智能染色内镜模式下联合卢戈染色组(D组)103例,并进行上皮乳头内毛细血管袢(IPCL)分型,取标本作病理检查,分析4种不同模式的检出情况。结果 D组对病变部位的检出率明显高于A组和B组,差异均有统计学意义(P<0.05);D组对早期食管癌及重度不典型增生的检出率略高于B组和C组,但差异无统计学意义(P>0.05);D组对轻度不典型增生的检出率明显高于A组和B组(P<0.05);D组对于中度不典型增生的检出率明显高于A组(P<0.05)。结论 FICE模式联合卢戈染色能够更清晰更快捷地显示早期食管癌及癌前病变的部位和范围,有助于进行更准确的活检,从而提高病变的检出率,进而更早、更准确的诊断出食管早癌及癌前病变。
Objective To compare the different modes of early diagnosis of esophageal cancer and precancerous lesions by using white light mode, FICE, Lugo staining and Lugo staining in FICE mode. value. Methods A total of 393 patients with lesions in the esophagus and biopsy underwent gastroscopy from 2015 to 2016 in our hospital were divided into 97 cases in the normal white light group (group A) (97 cases), 96 cases of Lugol’s stain group (Group C) and 103 cases of combined Lugol’s stain group (D group) under high-definition intelligent endoscopy. The specimens were divided into three groups: IPCL Specimens for pathological examination, analysis of four different modes of detection. Results The detection rate of lesion in group D was significantly higher than that in group A and group B (P <0.05). The detection rate of esophageal cancer and severe dysplasia in group D was slightly higher than that in group B (P> 0.05). The detection rate of mild dysplasia in group D was significantly higher than that in group A and group B (P <0.05). For group D, there was no significant difference The detection rate of hyperplasia was significantly higher than that of group A (P <0.05). Conclusion FICE mode combined with Lugol’s stain can display the location and extent of early esophageal cancer and precancerous lesions more clearly and quickly, which can help to carry out more accurate biopsy, so as to improve the detection rate of lesions and thus earlier and more accurate Diagnosis of esophageal cancer and precancerous lesions.