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本文对150例男性不育患者进行了精浆抗精子抗体检测与解脲支原体培养,发现抗精子抗体阳性组解脲支原体检出率为66.7%,抗精子抗体阴性组解脲支原体检出率为40.2%,两组之间存在显著性差异(P<0.005)。对抗精子抗体、解脲支原体均为阳性组进行了两种治疗方法的疗效对比,结果表明,使用抗生素组抗体转阴率为70%,未使用抗生素组抗体转阴率为36.4%,两组疗效存在显著性差异(P<0.05)。提出解脲支原体可能是导致男性免疫性不育的病因之一。认为积极治疗生殖道感染有助于降低抗体滴度,阻止抗体形成,对免疫性不育的治疗有重要意义。
In this study, 150 cases of male infertility were tested for seminal plasma anti-sperm antibodies and Ureaplasma urealyticum culture. The detection rate of Ureaplasma urealyticum was 66.7% in anti-sperm antibody positive group and Ureaplasma urealyticum was detected in anti-sperm antibody negative group The rate was 40.2%, there was a significant difference between the two groups (P <0.005). Anti-sperm antibodies, Ureaplasma urealyticum were positive group conducted a comparison of the efficacy of the two treatment methods, the results showed that the use of antibiotic antibody negative rate was 70%, unused antibiotic antibody negative rate was 36.4%, two There was significant difference between the two groups (P <0.05). Proposed Ureaplasma urealyticum may be one of the causes of male immune infertility. That active treatment of genital tract infection helps to reduce antibody titers, prevent the formation of antibodies, immune sterility treatment of great significance.