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一氧化氮（ＮＯ）是一种重要的、与炎症和免疫反应有关的分子，是一种神经元信息分子。一氧化氮和内皮素的生化特点表明了它们与青光眼的发病机理有关。本文着重叙述一氧化氮和内皮素在眼内压（ＩＯＰ）调节和眼部血循环以及程序性细胞死亡（凋亡，ａｐｏｐｔｏｓｉｓ）介导的视网膜神经节细胞死亡中的作用
Nitric oxide (NO) is an important molecule involved in inflammation and immune response and is a kind of neuronal information molecule. The biochemical characteristics of nitric oxide and endothelin suggest that they are associated with the pathogenesis of glaucoma. This review focuses on the role of nitric oxide and endothelin in the regulation of intraocular pressure (IOP) and ocular blood circulation and apoptosis of retinal ganglion cells (apoptosis)