~(111)In标记白细胞用于炎症的诊断引起人们的极大兴趣。由于~(111)In的物理半衰期(2.7天)极其适合这类研究,因此,在过去十年中用~(111)In连接了多种螯合剂。应用这种技术首先要求被标记后的白细胞具有完整的体内功能。作者比较了几种文献介绍的方法,找到了一种血小板含量很低和不含红细胞的白细胞是液制备方法。作者对三种常用的~(111)In螯合剂:~(111)In-8-羟 The detection of ~ (111) In-labeled leukocytes is of great interest for the diagnosis of inflammation. Since the physical half-life of (111) In (2.7 days) is well suited for this type of research, several chelators have been linked with ~ (111) In over the past decade. The application of this technique first requires that labeled leukocytes have intact in vivo functions. The authors compared several of the methods described in the literature to find a method for preparing leukocytes that have low platelet counts and no erythrocytes. The author of the three commonly used ~ (111) In chelator: ~ (111) In-8-hydroxy