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心肌肥厚是心血管疾病常见的临床症状，它与冠心病，心衰，脑卒中等疾病均密切相关，对其发生机制的探讨将为心肌肥厚及相关疾病的研究和治疗提供有益的线索。本实验以腹主动脉缩窄的左心室肥厚大鼠为模型，采用体外灌流分离心肌细胞，同时提取RNA并通过反转录来检查所得HNA的
Cardiac hypertrophy is a common clinical symptom of cardiovascular diseases. It is closely related to coronary heart disease, heart failure, stroke and other diseases. The study of its mechanism will provide useful clues for the study and treatment of cardiac hypertrophy and related diseases. In this study, a rat model of left ventricular hypertrophy with narrowing of the aorta was used. Cardiomyocytes were isolated by perfusion in vitro and RNA was extracted at the same time and the resulting HNAs were examined by reverse transcription