癌胚抗原125(CA125)又称卵巢相关抗原,作为一种肿瘤标志物,最初主要应用于卵巢癌的诊断和预后判断。近年来研究发现,在一些非妇科疾病(如胃癌、肠癌、肺癌)患者血清中CA125也有不同程度的增高,在呼吸系统疾病中CA125可作为肺癌诊断、病理分型及预后判断的重要参考指标,在一些良性呼吸系统疾病(如胸腔积液、肺结核)的诊疗过程中也有一定的应用价值。 Carcinoembryonic antigen 125 (CA125), also known as ovarian associated antigen, as a tumor marker, initially mainly used in ovarian cancer diagnosis and prognosis. In recent years, the study found that in some non-gynecological diseases (such as gastric cancer, intestinal cancer, lung cancer) serum CA125 levels have increased to varying degrees, in respiratory disease CA125 can be used as lung cancer diagnosis, pathological classification and prognosis of important reference indicators , In some benign respiratory diseases (such as pleural effusion, tuberculosis) diagnosis and treatment process also has some value.