论文部分内容阅读
环境内分泌干扰物是环境中存在的一类化学物质,包括的种类很多。动物实验表明,环境内分泌干扰物具有拟/抗雌激素、拟/抗雄激素、拟/抗甲状腺激素等活性,其中有拟雌激素活性或抗雄激素活性的占大多数,能够造成发育期动物内分泌、生殖功能改变,可引起幼年动物的生殖毒性。青春期儿童处于发育期,其下丘脑_垂体_性腺轴对进入体内的环境内分泌干扰物很敏感,因此,环境内分泌干扰物可能是引起青春期性发育异常的一个重要因素,在女孩主要表现为性早熟,在男孩主要表现为青春期延迟。
Environmental endocrine disrupters are a type of chemical that exists in the environment, including many types. Animal experiments show that environmental endocrine disruptors have quasi / anti-estrogen, anti-androgen / anti-and / anti-thyroid hormone activity, of which there is a pseudo-estrogen activity or anti-androgen activity accounted for the majority, can cause developmental animals Endocrine, reproductive changes, can cause juvenile reproductive toxicity. Adolescent children are in developmental stage, and their hypothalamus-pituitary-gonadal axis are sensitive to environmental endocrine disruptors entering the body. Therefore, environmental endocrine disruptors may be an important factor causing puberty dysplasia. When the girl is mainly characterized by precocious puberty , The main manifestation of the boy was delayed puberty.