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作者从加里福尼亚大学口腔内科门诊选择14名患者参予用左旋咪唑的双盲试验。根据口腔溃疡的慢性或复发特点,并结合所出现的红斑在临床及组织学和多形性红斑相同的表现,而且又不能证明是其他任何疾病者诊断为多形性红斑。研究组由10名男患者及4名女患者组成,发病年龄为18～76岁。患者罹病1～8年,平均4.7年。在本研究期间无一例病人使用类甾醇药物。本研究所选择的患者处于多形性红斑最严重时期。他们是由于大剂量强的松治疗失败,或是由于严重的副
The authors selected 14 patients from the University of California Department of Stomatology to participate in a double-blind trial of levamisole. According to the chronic or recurrent features of oral ulcers, combined with the appearance of erythema in clinical and histological and erythema multiforme the same performance, but can not prove that any other disease diagnosis of erythema multiforme. Study group consists of 10 male patients and 4 female patients, the age of onset was 18 to 76 years. Patients suffering from 1 to 8 years, an average of 4.7 years. None of the patients used steroid drugs during the study. The patients selected for this study were at the most severe stage of erythema multiforme. They are due to the failure of high-dose prednisone treatment or due to severe side effects