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目的探讨沙丁胺醇与布地奈德溶液雾化吸入治疗儿童毛细支气管炎的效果。方法选取2006年1月-2008年1月本院儿科住院的毛细支气管炎患儿90例,入院时均有阵发性咳嗽、喘憋、气促,肺部听诊有哮鸣音。随机分为对照组及治疗组,每组各45例。2组患儿均予常规治疗,治疗组在常规治疗的基础上予沙丁胺醇及布地奈德溶液泵雾化吸入。结果治疗组显效8例,有效35例,总有效率95.5%;对照组显效2例,有效33例,总有效率77.7%。2组总有效率比较有统计学差异(χ2=9.90,P<0.01)。治疗组咳喘消失时间、肺部喘鸣音消失时间及住院时间均少于对照组(Pa<0.01)。结论沙丁胺醇与布地奈德溶液泵雾化吸入治疗毛细支气管炎有协同作用,可明显改善症状及缩短病程,提高治愈率。
Objective To investigate the effect of salbutamol and budesonide solution on bronchiolitis in children. Methods From January 2006 to January 2008, 90 pediatric patients with bronchiolitis were admitted to our hospital for pediatric bronchitis. All patients had paroxysmal cough, wheezing, shortness of breath and wheezing on the lung during admission. Randomly divided into control group and treatment group, 45 cases in each group. Both groups were given routine treatment. The treatment group was given inhalation of salbutamol and budesonide solution pump on the basis of routine treatment. Results In the treatment group, 8 cases were markedly effective and 35 cases were effective. The total effective rate was 95.5%. In the control group, 2 cases were markedly effective and 33 cases were effective. The total effective rate was 77.7%. The total effective rate of 2 groups was statistically significant (χ2 = 9.90, P <0.01). Treatment group cough disappear time, pulmonary wheeze disappear time and hospitalization time were less than the control group (Pa <0.01). Conclusion Salbutamol and budesonide solution pump inhalation treatment of bronchiolitis has a synergistic effect, can significantly improve the symptoms and shorten the course of disease, improve the cure rate.