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患儿,女,3岁。11—07—03因发热,淋巴结肿大1个月而入院。患儿入院前2个月曾患“肺炎”,抗炎治疗7天治愈。1个月前患儿出现发热,全身浅表现淋巴结肿大,按“结核”治疗无效。入院前1周患儿出现持续高热,体温在40℃以上。查体:全身浅表淋巴结肿大,最大约1.5cm×1.5cm,无触痛,活动度可,咽部充血。肝右肋下4.0cm,脾肋下3.0cm。质中等硬。心、肺、神经系统正常。实验室检查,白细胞26×10~/L。分叶76%,淋巴20%,异淋4%。肝功、血沉、肥达氏反应均正常。OT试验阴性。血培养:香气黄杆菌(+)。X线平片:肺纹理增强,肺门影大。骨髓回报;反应性粒细胞增多。诊断:黄杆菌败血症。治疗:静点先锋霉素VI、氨基苄青霉系、庆大霉素、红霉素,共治疗15天病情无缓解,转院治疗。细菌分离:血培养3天,肉汤出现混浊,转种血平板,经35℃、24h培养,菌落呈圆形、光滑、稍凸,产生脂溶性黄色素,并有水果香味。菌落大小为1.5mm
Children, female, 3 years old. 11-07-03 Due to fever, lymphadenopathy 1 month and admitted to hospital. Two months before admission to hospital children had “pneumonia”, anti-inflammatory treatment for 7 days to cure. 1 month ago, children with fever, generalized lymphadenopathy, according to “tuberculosis” treatment ineffective. One week before admission, the patient showed sustained high fever, body temperature above 40 ℃. Physical examination: systemic superficial lymph nodes, the largest about 1.5cm × 1.5cm, no tenderness, activity, throat congestion. Liver right rib 4.0cm, spleen ribs 3.0cm. Medium hard. Heart, lung, nervous system normal. Laboratory tests, white blood cells 26 × 10 ~ / L. 76% leaves, lymph 20%, different leaching 4%. Liver function, erythrocyte sedimentation rate, Widal reaction were normal. OT test negative. Blood culture: Flavobacterium flavum (+). X-ray: lung enhancement, hilar shadow. Marrow return; reactive granulocytes. Diagnosis: Flavobacterium sepsis. Treatment: Static point cephalosporin VI, ampicillin, gentamicin, erythromycin, a total of 15 days of treatment without remission, transfer treatment. Bacteria isolated: blood culture for 3 days, the broth appeared turbid, transplanted blood plate, after 35 ℃, 24h culture, colonies were round, smooth, slightly convex, resulting in fat-soluble yellow pigment, and fruit flavor. The colony size is 1.5mm