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目的:探讨肺炎支原体(Mp)感染与小儿慢性咳嗽的关系。方法:对确诊的150例慢性咳嗽小儿和对照组126例小儿采用ELISA方法定性检测慢性咳嗽患儿血清中的Mp特异性IgM抗体,并进行组间比较。结果:150例慢性咳嗽患儿中,Mp-IgM阳性46例,阳性率30.60%,对照组126例患儿中,MP-Ab阳性15例,阳性率11.90%,两组比较差异有统计学意义。结论:Mp感染可能是小儿慢性咳嗽的主要原因。
Objective: To investigate the relationship between Mycoplasma pneumoniae (Mp) infection and chronic cough in children. Methods: The serum Mp-specific IgM antibodies in 150 children with chronic cough and 126 children with chronic cough were detected by ELISA. The serum levels of Mp-specific IgM antibodies in children with chronic cough were compared. Results: Of the 150 children with chronic cough, Mp-IgM was positive in 46 cases and the positive rate was 30.60%. Among 126 children in the control group, MP-Ab was positive in 15 cases and the positive rate was 11.90%. There was significant difference between the two groups . Conclusion: Mp infection may be the main reason for chronic cough in children.