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目的了解胸腔内注射红霉素治疗顽固性胸腔积液的临床作用。方法将３４例顽固性胸腔积液病例分成２组，分别在抽水后给予红霉素或其它药物胸腔内注射，并根据抽胸水及注药３次后胸水基本吸收的例数、全部胸水吸收所需时间来评估。结果２组３次抽水及注药后胸水基本吸收的有效率分别是８６．６７％和６３．１６％（Ｐ＜０．０５），且红霉素组胸水吸收时间短于其它药物组（Ｐ＜０．０５）。结论红霉素胸腔内注射治疗顽固性胸腔积液疗效较佳。
Objective To investigate the clinical effect of intrapleural injection of erythromycin in refractory pleural effusion. Methods 34 cases of intractable pleural effusion were divided into two groups, respectively, after injection of erythromycin or other drugs given intrathoracic injection, and according to the pleural effusion and injection of three cases of pleural effusion after the basic absorption of the total number of pleural effusion Take time to evaluate. Results The effective rate of pleural effusion and absorption of pleural effusion after three injections were 86.67% and 63.16% respectively (P <0.05), and the pleural effusion time in erythromycin group was shorter than that in other drugs (P <0.05). Conclusion Erythromycin intrapleural injection of intractable pleural effusion is better.