新生儿ABO溶血是新生儿溶血病中最常见的病种之一,严重者可导致胆红素脑病,直接威胁患儿生命质量。换血疗法是治疗新生儿重度溶血最迅速、有效的方法。传统的换血方法是采用“O型红细胞悬液+AB型血浆”的混合血,但因O型红细胞悬液红细胞压积较低,且其中混杂部分抗A或抗B血型抗 Neonatal ABO hemolysis hemolytic disease is one of the most common neonatal disease, severe cases can lead to bilirubin encephalopathy, a direct threat to children’s quality of life. Transfusion therapy is the most rapid and effective treatment of neonatal severe hemolysis. Traditional exchange method is to use “O-type erythrocyte suspension + AB plasma” mixed blood, but O-type erythrocyte suspension hematocrit lower, and mixed part of the anti-A or anti-B blood group anti