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目的了解广州地区≥15岁居民骨关节炎(osteoarthritis,OA)的流行病学特征及危险因素,为该病的早期预防及干预提供科学依据。方法运用多阶段整群抽样方法,抽取广州市9 600户家庭,对抽中家庭的≥15岁居民进行问卷调查和体格检查,分别采用X2检验和多因素Logistic回归分析分析不同群体OA的分布和居民患病的危险因素。结果共调查≥15岁居民23 994人,OA总自报患病率为2.5%(604/23 994);≥65岁居民OA自报患病率为6.7%(223/3 336);男女OA自报患病率分别为1.6%(189/11 783)和3.4%(414/12 146)。多因素Logistic回归分析显示,高年龄、女性、离退休人员、蔬菜摄入量≥300 g/d、饮食口味偏重、长期饮用山泉水、患有高血脂以及向心性肥胖是居民患OA的独立危险因素。结论广州地区≥15岁人群总体自报患病率较低,应加强各社区高危人群筛查。适度的体力活动、合理的饮食习惯、控制体重和防治高血脂是预防控制骨关节炎的主要措施。
Objective To understand the epidemiological characteristics and risk factors of osteoarthritis (OA) in residents aged 15 or above in Guangzhou, and to provide scientific evidence for the prevention and intervention of this disease. Methods A multistage cluster sampling method was used to sample 9 600 households in Guangzhou and questionnaires and physical examinations were performed on residents aged 15 or older who were among the sampled families. X2 test and multivariate Logistic regression analysis were used to analyze the distribution of OA among different groups Residents risk factors. Results A total of 23 994 residents aged 15 and over were surveyed. The prevalence of self reported OA was 2.5% (604/23 994). The self reported self reported positive rate was 6.7% (223/3 336) The reported prevalences were 1.6% (189/11 783) and 3.4% (414/12 146), respectively. Multivariate logistic regression analysis showed that residents with high risk of OA had higher risk of inhabitants exposure to high age, female, retiree and vegetable intake≥300 g / d with a long-term consumption of spring water, hyperlipidemia and central obesity factor. Conclusions The overall prevalence rate of ≥15 years old in Guangzhou is lower than that in Guangzhou. Screening of high-risk groups should be strengthened in all communities. Moderate physical activity, a reasonable diet, weight control and prevention and treatment of hyperlipidemia are the main measures to prevent and control osteoarthritis.