论文部分内容阅读
目的:观察通心络胶囊对老年缺血性卒中患者认知功能及血脂的影响,以及治疗前后MoCA、ADL评分变化。方法:按照诊断标准、纳入标准、排除标准筛选出符合观察的病例60例,随机分为治疗组与对照组,每组各30例,比较两组治疗前后LDL-C、Apo-A1、Apo-B、Apo-B/Apo-A1的含量变化,以及MoCA、ADL的积分变化情况。结果:两组之间疗效比较,治疗组优于对照组(P<0.05);LDL-C:治疗后两组比较,P<0.01;Apo-A1:治疗后两组比较,P<0.05;Apo-B:治疗后两组比较,P<0.01;Apo-B/Apo-A1:治疗后两组比较,P<0.01。结论:通心络胶囊能改善老年缺血性卒中患者的认知功能,提高MoCA、ADL积分,降低LDL-C、Apo-B的水平,升高Apo-A1含量,降低Apo-B/Apo-A1的比值。
Objective: To observe the effect of Tongxinluo Capsule on cognitive function and blood lipids in elderly patients with ischemic stroke and the changes of MoCA and ADL scores before and after treatment. Methods: According to the diagnostic criteria, included in the standard, exclude the standard screening of 60 cases in line with the observation, were randomly divided into treatment group and control group, 30 cases in each group. The levels of LDL-C, Apo-A1, Apo- B, Apo-B / Apo-A1 content changes, and MoCA, ADL integral changes. Results: The curative effect of the two groups was better than that of the control group (P <0.05); LDL-C: P <0.01 after treatment; Apo-A1: P < B: P <0.01 after treatment; Apo-B / Apo-A1: P <0.01 after treatment. Conclusion: Tongxinluo capsule can improve cognitive function, increase MoCA and ADL score, lower LDL-C and Apo-B levels, increase Apo-A1 content and decrease Apo-B / Apo- A1 ratio.