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[目的]探讨甲醛对作业工人免疫系统的影响。[方法]调查分析昆山市存在甲醛职业危害的企业,选择65名甲醛作业工人和非甲醛暴露工人70名为研究对象,采集工人静脉血,经仪器自动分析,测定作业工人血清补体C3、C4及血清免疫球蛋白IgA、IgG、IgM。[结果]18家企业甲醛最高浓度达3.11mg/m3,超标作业点达29.09%。暴露组作业工人血清补体C3(0.99±0.31)、IgM(1.16±0.51);≥5年组作业工人血清补体C(30.85±0.15)、C4(0.20±0.05)及血清IgA(1.28±0.57)、IgM(0.90±0.35)明显降低,与对照组比较差异有统计学意义(P<0.01)。[结论]接触甲醛导致作业工人免疫功能抑制。
[Objective] To investigate the effect of formaldehyde on workers’ immune system. [Methods] To investigate and analyze the enterprises with occupational hazards of formaldehyde in Kunshan City, 65 workers with formaldehyde and 70 workers with non-formaldehyde exposure were selected to study the venous blood collected from the workers. The serum C3, C4 and Serum immunoglobulin IgA, IgG, IgM. [Result] The highest concentration of formaldehyde in 18 enterprises reached 3.11mg / m3, 29.09% exceeded the standard of operation. Serum complement C3 (0.99 ± 0.31) and IgM (1.16 ± 0.51) in exposed workers and serum complement C (30.85 ± 0.15), C4 (0.20 ± 0.05) and serum IgA (1.28 ± 0.57) IgM (0.90 ± 0.35) was significantly lower than the control group, the difference was statistically significant (P <0.01). [Conclusion] The exposure of formaldehyde caused the workers to suppress the immune function.