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目的：探讨普罗帕酮与胺碘酮治疗阵发性室上性心动过速（PSVT）的临床疗效及安全性有无差别。方法2011年2月～2013年4月我院收治的65例PSVT患者进行回顾性分析，其中采用普罗帕酮治疗患者31例（普罗帕酮组），采用胺碘酮治疗患者34例（胺碘酮组），分析比较两组患者窦性心律转复成功率、转复时间及不良反应发生率有无差别。结果普罗帕酮组与胺碘酮组成功转复窦性心律分别为25（25/31）例和28（28/34）例，两组患者成功率差别无统计学意义（P＞0.05）；普罗帕酮组转复时间为8.02±3.21min，胺碘酮组为14.66±5.29min，胺碘酮组转复时间显著高于普罗帕酮组（P＜0.05）；两组患者不良反应发生率差别无统计学意义（P＞0.05）。结论普罗帕酮与胺碘酮治疗PSVT临床有效率及副反应无明显差别，但胺碘酮组转复时间显著延长。“,”Objective To evaluated the clinical efficacy and side effects of propafenone and amiodarone in the treatment of patients with paroxysmal supraventricular tachycardia(PSVT).Methods Sixty-six subjects with PSVT from Feb 2011 to Apr 2013 were recruited and retrospectively analyzed.Of the66 included patients,31 cases was treated with propafenone and other 34 treated with amiodarone.Comparition of the termination rate and adverse events rate were observed between the two groups.Results The successfully converting sinus rhythm rate of propafenone group and amiodarone group were 25 cases (25/31) and 28 cases (28/34) respectively,with no statistically significant difference between the two groups (P>0.05);The time of heart beat recovery in propafenone group were 8.02±3.21 min and amiodarone group 14.66±5.29 min with demonstrated that much time for amiodarone group was found with statistical significance(P0.05).Conclusion Administration of Amiodarone and Propafenone is efficient and safe in the treatment of PSVT.