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目的观察杜仲壮骨丸联合西药治疗活动性强直性脊柱炎的疗效。方法选取48例强直性脊柱炎患者,随机分成两组,对照组24例予服沙粒度胺、来氟米特、醋氯芬酸缓释片,治疗组24例在对照组治疗基础上加用杜仲壮骨丸,比较两组疗效;并随访1年,观察两组1年内病情复发情况。结果治疗组总有效率92%,对照组总有效率74%,两组疗效比差异有统计学意义(P<0.05),治疗组疗效优于对照组。在炎症指标ESR、CRP治疗后自身对照均有显著性差异(P<0.05),但两组组间比较未见明显差异(P>0.05),随访1年中对照组病情缓解后复发并加重4例,治疗组无反复。结论在西医常规治疗的基础上加用杜仲壮骨丸治疗强直性脊柱炎有更理想的疗效。
Objective To observe the curative effect of Duzhong Zhuanggu Wan combined with Western medicine in treating active ankylosing spondylitis. Methods Forty-eight patients with ankylosing spondylitis were randomly divided into two groups. The control group received gatifloxacin, leflunomide, and aceclofenac sustained-release tablets. The treatment group was given 24 patients on the basis of the control group Eucommia Zhuanggu Wan, the two groups were compared; and followed up for 1 year, two groups were observed within 1 year of disease recurrence. Results The total effective rate was 92% in the treatment group and 74% in the control group, the difference between the two groups was statistically significant (P <0.05). The curative effect in the treatment group was better than that in the control group. There were significant differences between the two groups (P> 0.05). There was no significant difference between the two groups (P> 0.05). After one year of follow-up, the control group recurred and aggravated 4 For example, the treatment group without repetition. Conclusion Western medicine on the basis of conventional treatment plus Duzhuang Zhuanggu Wan treatment of ankylosing spondylitis has a more satisfactory curative effect.