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目的:通过分析慢性阻塞性肺疾病(COPD)急性加重次数与肺功能、体重指数、年龄、性别的相关性,探讨COPD急性加重次数的影响因素。方法:COPD患者住院治疗后病情稳定出院时,收集其年龄、性别、肺功能[第1秒用力呼气量(FEV)1、用力肺活量(FVC)]、体重指数的资料,随访1年,督促规范随诊治疗,观察急性加重次数,分析COPD急性加重次数的影响因素。结果:采用多因素线性回归分析,COPD的急性加重次数与性别、年龄、FEV1、1秒率(FEV1/FVC%)无相关性,与体重指数及FEV1占预计值百分比(FEV1%)呈负相关。结论:应减缓肺功能的下降,改善营养状况,才能减少COPD急性加重次数。
Objective: To investigate the influencing factors of acute exacerbation of COPD by analyzing the correlation between acute exacerbations of chronic obstructive pulmonary disease (COPD) and pulmonary function, body mass index, age and gender. Methods: COPD patients were hospitalized for stable disease after hospital discharge, and their age, sex, pulmonary function [FEV 1, FVC] and body mass index were collected and followed up for 1 year. Standard follow-up treatment, observe the number of acute exacerbations, analyze the influencing factors of acute exacerbation of COPD. Results: The multivariate linear regression analysis showed that there was no correlation between the number of acute exacerbations of COPD and gender, age, FEV1, 1-second rate (FEV1 / FVC%), and body mass index and FEV1 percentage of predicted value . Conclusion: It is necessary to reduce the decline of lung function and improve the nutritional status in order to reduce the number of acute exacerbations of COPD.